Meta-analysis for rare events
نویسندگان
چکیده
منابع مشابه
Meta-analysis for rare events.
Meta-analysis provides a useful framework for combining information across related studies and has been widely utilized to combine data from clinical studies in order to evaluate treatment efficacy. More recently, meta-analysis has also been used to assess drug safety. However, because adverse events are typically rare, standard methods may not work well in this setting. Most popular methods us...
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Meta-analysis of rare event studies has recently become a subject of controversy and debate. We will argue and demonstrate in this paper that the occurrence of zero events in clinical trials or cohort studies, even if zeros occur in both arms (the case of a double-zero trial), is less problematic, at least from a statistical perspective, if the available statistical tools are applied in the app...
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In many areas of engineering and science there is an interest in predicting the probability of rare events, in particular in applications related to safety and security. Increasingly, such predictions are made through computer models of physical systems in an UQ framework. Additionally, with advances in IT, monitoring and sensor technology, more and more data on the performance of the systems i...
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There are miscellaneous quality characteristics in healthcare which are interested to be monitored. However, monitoring each characteristic needs a special statistical method. There are some characteristics with very small incidence rates that it’s usually considered not to be necessary to monitoring them, since their incidence rates are so small that p and np charts are not able to monitor t...
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It has been claimed that corpus-based TTS is unworkable because it is not practical to include representative units to cover all or most of the combinations of segments and prosodic characteristics found in general texts, a problem characterized as Large Numbers of Rare Events (LNRE). We argue that part of this problem is in its formulation, and that a closer look, including investigations into...
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ژورنال
عنوان ژورنال: Statistics in Medicine
سال: 2010
ISSN: 0277-6715
DOI: 10.1002/sim.3964